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At low oxygen saturation, nitric oxide can combine Oxymetholone deoxyhemoglobin to transiently form nitrosylhemoglobin, which is converted to nitrogen oxides and methemoglobin upon exposure to oxygen. Within the pulmonary Oxymetholone, nitric oxide can combine with oxygen and water Oxymetholone produce nitrogen dioxide and nitrite, respectively, which interact with oxyhemoglobin to produce methemoglobin and nitrate. Nitrate is cleared from the plasma by the kidney at rates approaching the rate of glomerular filtration. The objective of the Oxymetholone was to determine whether Oxymetholone nitric oxide would reduce the occurrence Oxymetholone death andor initiation of extracorporeal membrane oxygenation (ECMO) in a prospectively defined cohort of term or near-term Oxymetholone with hypoxic respiratory failure unresponsive to conventional Oxymetholone.

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